Understanding and Managing Hair Loss During GLP‑1 Weight‑Loss Therapy

One surprising side effect some people notice while using GLP‐1 medications like Ozempic®, Wegovy®, Mounjaro® or Zepbound® is hair loss. This phenomenon has been dubbed “Ozempic hair” on social media, but it isn’t unique to GLP‐1s and isn’t an FDA‐listed side effect. Instead, experts explain that rapid weight loss and nutritional deficiencies trigger a temporary form of hair shedding called telogen effluvium. This blog explores why hair loss happens, how to prevent it, and effective treatments to restore healthy hair.

Losing weight quickly can be perceived as a physiological stressor. When the body enters preservation mode, more hair follicles shift from the growth phase into the resting (telogen) phase and are shed a few weeks to months later. Board‐certified dermatologist Dendy Engelman, MD, notes that people often don’t notice hair loss until they’ve lost about half of their hair density.

GLP‐1 drugs suppress appetite and slow gastric emptying, which can reduce overall food intake. Deficiencies in protein, iron, zinc, B‐vitamins, copper and vitamin D are common triggers for telogen effluvium. Cleveland Clinic endocrinologist Dr. Kathy Zhou warns that eating less without focusing on nutrient density can lead to malnutrition and hair loss.

Rapid weight loss and caloric restriction can also alter thyroid function and hormone levels, contributing to shedding. Fortunately, this hair loss is usually temporary and reversible when the underlying stressor is addressed.

Dr. Zhou recommends a slow‐and‐steady approach to weight loss to minimize shock to the system. Aim for sustainable calorie deficits rather than extreme restriction, and discuss safe weight‐loss targets with your provider.

Even when eating less, your meals should be rich in protein and essential vitamins and minerals. Focus on:

• Lean proteins (chicken, fish, tofu, beans) – hair is made of keratin, a protein.
• Iron and zinc‐rich foods (red meat, spinach, lentils, pumpkin seeds) to support hair follicle function.
• B‐vitamins and biotin from eggs, nuts, seeds and whole grains.
• Vitamin D and copper sources, such as fatty fish, mushrooms and nuts, which support hair growth.
• Hydration – staying well hydrated prevents dehydration‐related shedding and supports overall metabolism.

Supplements can help fill nutrient gaps, but choose evidence‐based products. Dermatologists in The Cut article recommend Nutrafol and Viviscal, which have clinical data supporting improved hair density. Consult your healthcare provider before starting supplements, especially if you are on other medications.

• Minoxidil: The only FDA‐approved medication for regrowing hair; topical solutions must be applied twice daily, while low‐dose oral minoxidil is gaining popularity for ease of use.
• PRP (platelet‐rich plasma) therapy: Involves injecting concentrated platelets into the scalp to stimulate growth; typically performed every 4–6 weeks for several months.
• Red‐light therapy: Home devices like LED helmets can promote scalp circulation and support hair health.
• Topical serums: Oils such as argan or formulas like Nulastin may improve hair condition, but experts emphasize these are supportive measures and not standalone fixes.

Hair growth is slow. You’ll first notice reduced shedding, followed by gradual regrowth over 6–12 months, and full recovery can take longer. Calming anxiety around hair loss is important because stress can exacerbate shedding.

• Persistent or severe hair loss. If shedding continues beyond a year or leaves bald patches, consult a dermatologist to rule out other causes (androgenic alopecia, alopecia areata).
• Nutritional deficiencies. Have your provider check iron, ferritin, zinc, vitamin D and thyroid levels; correcting deficiencies often resolves telogen effluvium.
• Psychological distress. Hair loss can impact self‐esteem. Counseling or support groups may help manage emotional stress, which in turn can reduce shedding.

• Hair shedding with GLP‐1 therapy is usually due to rapid weight loss, not the medication itself. It commonly manifests 2–3 months after weight loss begins and is reversible once nutritional status and weight stabilize.
• Prevent loss by eating nutrient‐dense meals, supplementing wisely and losing weight gradually.
• ●  Use evidence‐based treatments such as minoxidil, PRP and red‐light therapy, and be wary of unproven serums or “miracle” products.
• Allow time for regrowth—hair may take six to twelve months to return to normal.

At Fountain of Youth MedSpa, we offer medical weight‐loss programs and hair‐restoration treatments such as PRP therapy and low‐level laser therapy. If you’re concerned about hair shedding during GLP‐1 treatment, book an appointment to explore personalized solutions.